Processing math: 100%

Compute the MLE for parasite counts data

counts_MLE(alpha, counts, inits, F_b, F_Sa, q = 6, bvm = 13, SANN = FALSE)

Arguments

alpha

the ages of infection

counts

the counts

inits

the initial guesses for the parameters

F_b

a function to constrain the upper bound for fitting for Fmu

F_Sa

a function to constrain the slope for fitting for Fmu

q

the sampling volume (in log10microliters)

bvm

the blood volume (in log10microliters)

SANN

if true, then use simulated annealing

Value

the fitted parameter values and the log likelihood